Spreading the Disease is the second studio album by American heavy metal band Anthrax and the first with vocalist Joey Belladonna and bassist Frank Bello. The album was released in October 1985 by Megaforce Worldwide/Island in the United States and in March 1986 by Island Records globally.
The band produced the album with Carl Canedy, Jon Zazula serving as executive producer. The album includes the single "Madhouse". A music video was produced for "Madhouse" as well, but didn't receive much airplay because it was banned by MTV, who believed the content to be degrading to the mentally ill.
This was the last Anthrax album to feature songwriting from fired vocalist Neil Turbin, who is given songwriting credit on the songs "Armed and Dangerous" and "Gung-Ho". Songwriting credit was shared to the track "Medusa", the first and only songwriting contribution from former producer Jon Zazula. Originally he was credited as the sole writer of the song, but reissues credited the rest of the band to it as well.
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